منابع مشابه
Generalized choreiform movements as a complication of methyldopa therapy in chronic renal failure.
Introduction Although methyldopa has been widely used in the treatment of hypertension for many years there is only a single case report (Yamadori and Albert, 1972) of bilateral choreoathetotic movements possibly related to treatment with this drug. That isolated case report was of a patient with concomitant severe bilateral cerebrovascular disease. The authors report here a similar case but in...
متن کاملAlpha-methyldopa hepatotoxicity in pregnancy.
A 12-week pregnant, 33-year-old African American female, presented with jaundice and change in urine colour. Liver function tests revealed raised transamines and normal alkaline phosphatase. She was started on methyldopa 6 weeks prior to presentation. After initial negative investigations including viral and autoimmune hepatitis, she was given prednisone for methyldopa induced hepatitis. Two we...
متن کاملHepatic injury caused by L-alpha-methyldopa.
a rise in serum alkaline phosphatase, glutamic oxaloacetic transaminase levels, and increased Bromsulphalein retention. Elevation of the serum bilirubin may occur. In its most benign form the condition is usually symptomless, but complaints, such as anorexia, abdominal pain, or pruritus, and signs, such as fever or hepatomegaly, may occur. Histologic changes similar to those of viral hepatitis ...
متن کاملBronchial asthma due to alpha-methyldopa.
iron-storage disease, malignant disease, and a history of neck surgery or irradiation. Bone biopsy was not performed in either case because of the absence of any biochemical or radiological evidence of osteomalacia. Our first case is the oldest known patient to present with this disorder, the oldest described elsewhere being an 80-year-old man who presented with confusion.4 Little is known abou...
متن کاملAlpha-methyladrenaline: a possible active metabolite of alpha-methyldopa in the rat brain.
To determine whether or not alpha-methyladrenaline (MA) is an active metabolite of alpha-methyldopa, a centrally-acting hypotensive compound, we measured MA in the rat brain using the high-performance liquid chromatographic electrochemical detection method. After five daily treatments of alpha-methyldopa given twice daily a dose of 40 mg/kg, we found trace amounts of MA in the hypothalamus and ...
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ژورنال
عنوان ژورنال: Anaesthesia and Intensive Care
سال: 1974
ISSN: 0310-057X,1448-0271
DOI: 10.1177/0310057x7400200211